Cy7-N-羥基琥珀酰胺酯|CAS 477908-53-5|Sulfo-cyanine7 NHS ester

Cy7-N-羥基琥珀酰胺酯|CAS 477908-53-5|Sulfo-cyanine7 NHS ester

產品簡介

胺類活性染料,近紅外熒光染料,Cy7?的改進的類似物。近紅外熒光素可以被用來利用生物組織的近紅外窗口。在這個光譜區域,高度增強的組織透明度使得活體成像成為可能。該染料可用于制備CY7標記的生物分子來進行后續試驗,如活體研究及藥物開發相關實驗。Cy7的特殊結構加固了中心聚亞甲基(polymethyne)鏈的穩定性。這種增強的分子結構會使其量子產率較其母結構提供20%,因此它的熒光強度會更大。

該試劑在標記時需要共溶劑有機溶劑。水溶Cy7 NHS ester可以用于蛋白NIR標記。

Amine reactive Cyanine7, near infrared fluorescent dye, an improved analog of Cy7?.

NIR fluorophores can be used to take advantage of near infrared window of biological tissues – increased transparency of tissues in this spectral region allows to carry out in vivo imaging.

This reagent can be utilized to produce Cyanine7-labeled biomolecules for subsequent use in various in vivo research, and drug design related experiments.

The structure of Cyanine7 features rigidized design of central polymethyne chain. This molecular reinforcement allows to increase quantum yield by 20% compared with parent structure, increasing fluorescence brightness.

This reagent requires organic co-solvent for the labeling (please see Recommended Protocols section below). Water-soluble Cyanine7 NHS ester is also available, and recommended for protein NIR labeling.

一般特性

?外觀: green powder
分子量: 682.29
分子式: C41H48ClN3O4
溶解性: soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility ? in water
質量控制: NMR 1H (95%) and 13C, TLC, functional testing
儲存條件: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for ? up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

光譜特性

激發波長, nm: 750
在激發波長下的消光系數, Lmol-1cm-1: 199000
發生波長, nm: 773
熒光量子產率: 0.3